Miguel Perez-Pinzon, Ph.D., FAHA, Chair, International Stroke Conference 2019 Program Committee, offers overviews and perspective on late breaking science being presented at ISC 2019 in Honolulu. He is Professor of Neurology/Neuroscience, Director, Cerebral Vascular Disease Research Center, Director, Peritz Scheinberg Cerebral Vascular Laboratory, Vice-Chair for Neurology Basic Science at the Miller School of Medicine, Department of Neurology at the University of Miami, Miami, FL. copyright American Heart Association "The second part of MIS D3 was the surgical results. The efficiency, this was the efficiency of hemorrhage removal determined by MRI's. So here going back again, this is the same trial and this trial they assess whether greater removal of blood at the surgery in, in this MIS D3 trial impacted the likelihood of better functional outcomes after one year. And factors are linked to greater efficiency of blood removal. So in this trial, greater isage reduction had a higher likelihood of achieving a good outcome in the modified rankings score. And it was linked to the decrease in volume reduction. So this is the first trial to report a threshold for, the threshold for reduction of ICH volume linked will improve functional outcomes. And basically the benefit of this surgery and the protocol objectives, and educating these surgeons to do the technique better is basically the goal of this trial."